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Seeking information about the gall bladder, bile duct and cancer can feel overwhelming or frightening, especially if you’re unsure about what’s ahead for you or a loved one. Having the right information can help lessen some of these feelings. Here you will find reliable information about the gall bladder, bile duct, gallbladder cancer and bile duct cancer along with diagnosis, symptoms, risks, treatment, side effects, diet and nutrition and some useful websites to visit.<


Nau mai rā, rarau mai rā ki tēnei whārangi mō ngā kōrero e pā ana ki te mate pukupuku kouawai me te pūwaiate.

About the gallbladder & bile duct

Mō te kouawai me te pūwaiate


Gallbladder | Kouawai:

The gallbladder is a small pouch that stores and concentrates bile that is made by the liver. When bile is needed (i.e., when people eat) the gallbladder contracts and bile from the liver passes down the bile ducts into the small intestine where it aids with the digestion of fats.

Bile ducts | Pūwaiate:

Bile ducts are tubes that transport bile produced by the liver into the small intestine. There are two bile ducts that come from the liver and one from the gallbladder. These tubes connect to form the common bile duct that connects to the small intestine. When food is being digested, bile stored in the gall bladder is released and passed through the bile ducts into the small intestine.

Click here to view a diagram of the gallbladder and bile duct | Pāwhirihia ki kōnei kia tirohia he hoahoa whakaahuahanga o te kouawai me pūwaiate

What is gallbladder and bile duct cancer? | He aha tēnei mea te mate pukupuku kouawai, pūwaiate?

There are several types of gallbladder and bile duct cancers, named after the type of cell it affects. The gallbladder is lined by the same type of cells that line the bile ducts, therefore gallbladder cancer is similar to bile duct cancer.

Gallbladder cancer | Mate Pukupuku kouawai

Gallbladder cancer begins in the mucosal inner layer of the gallbladder and spreads through the outer layers. More than 85% of gallbladder cancer types are adenocarcinomas that start in the gland cells lining the gall bladder. The role of the gland cells is to produce mucous, a thick fluid that coats the lining of the gallbladder tissue.

Bile Duct Cancer (also known as cholangiocarcinoma) | Mate pukupuku pū waiate

Cholangiocarcinoma can form anywhere along the bile ducts and each sub-type of biliary tract cancer is named after the location where the primary cancer begins.

  • intrahepatic cancers begin inside the bile duct in the liver

  • extrahepatic cancers begin from bile ducts outside the liver

  • klatskin tumours account for half of bile duct cancers which form where the right hepatic duct joins with the left hepatic duct in the liver

  • common bile duct cancers begin in the common bile duct

  • multifocal bile duct cancer is when there are multiple tumours present in different areas of the bile duct.

Ampullary cancer


Ampullary cancer develops in the ampulla of Vater, where bile ducts from the liver and pancreas join and enter the duodenum.

Duodenal cancer

Duodenal cancer develops in the duodenum, the first and shortest part of the small bowel (e.g. small intestine), between the stomach and jejunum.

Symptoms & Risks

Tohumate & Tūraru


Common symptoms of gallbladder and bile duct cancer | Ngā tohumate tōkau o te mate pukupuku kouawai me te pūwaiate

Unexplained symptoms can be worrying for anyone. Here you will find information about some common symptoms of gall bladder and bile duct cancer and how to manage them. It is important to note that having one or more of these symptoms does not necessarily mean that you have cancer, but if you have new or persistent symptoms that are out of the ordinary for you, it’s really important that you contact your GP to get checked out.

Symptoms of biliary tract cancers are often vague or mistaken for other illnesses.

Click here to see common symptoms of gallbladder and bile duct cancer | Pāwhirihia ki kōnei kia tirohia ngā momo tohumate tōkau o te Mate Pukupuku Kouawai me te Pū waiate

Common symptoms of gallbladder or bile duct cancer may include:

  • jaundice (yellowing of the skin and whites of the eyes) due to obstruction to the flow of bile out of the liver

  • unexplained nausea and vomiting

  • unexplained weakness or fatigue/tiredness

  • unexplained loss of appetite and weight loss

  • fevers and chills

  • pain in the right side of the abdomen

  • darkened urine

  • pale bowel movements

  • itchy skin.

Managing symptoms | Whakahaere i ngā tohumate

You might notice that things change for you physically and emotionally following your diagnosis and you may have even noticed some of these symptoms prior to diagnosis. Understanding them can help you to prepare for them mentally and manage them if they do appear. If you do experience any of these symptoms, let your healthcare team know when you next see them. If they are extreme, or you are worried about them, get in touch with your healthcare team sooner.

Click below to learn about some ways you can manage these changes or symptoms | Pāwhirihia te momo tohumate mō ētahi atu mōhiohio.

Changes in diet | Ngā panonitanga o te whiringa Kai

Many people find that sorting out symptoms related to their diet makes the biggest difference to how they feel. Ask your doctor or nurse for a referral to a dietitian. They can help you with finding food to eat that is gentle on your digestive system.

Nausea | Whakapairuaki

Feeling sick (nauseous) is another common symptom. You may be prescribed anti-sickness medication, or you could try home remedies such as ginger, peppermint, or acupressure bracelets.

Fatigue | Ruha

You are bound to feel tired or exhausted sometimes, so be kind to yourself. Make sure you rest and prioritise what you want or need to do. Give yourself permission to accept offers of help for chores that feel overwhelming. Although you might not feel like it, gentle exercise such as stretching, or a short walk can help combat fatigue.

Intimacy | Mateoha

People of all genders can lose interest in sexual activity during cancer treatment, at least for a time. Although it can feel awkward, talking to your partner about what you find intimate, or soothing can help. There are many ways to be intimate, such as cuddling or gentle touch, or using warmth and comforting language. Your GP may be able to assist with medication or a referral to see a sex and relationship therapist.

Stress, pain, and anxiety | Kohuki, Mamae, Anipā

Simple relaxation techniques can help you cope with stress, pain, and anxiety. Having a warm bath, deep breathing or listening to soothing music are easy things to do at home. You might want to try complementary therapies like reflexology or aromatherapy massage. Talking to others can also help. There are many cancer-specific psychologists available to you in New Zealand – ask your oncologist, nurse, or GP for a referral.

Keep perspective | Kia whakataurite

Each individual will feel and react differently to treatment. What might work for someone else may not always work for you. Acknowledge that not every day will be as easy to manage as the last, and that every day may be different. Focus on what you know works for you and be very gentle with yourself.

Keeping active | Kia kori

Physical activity can also make you feel better, though how much activity will depend on how well you feel. Even a walk round the block or 10 minutes of stretching each day can help.

Risks of developing gallbladder and bile duct cancer |Ngā tūraru whakawhanake mate pukupuku kouawai me te pūwaiate

There are some known risk factors that can increase the chance of gallbladder and bile duct cancer developing. Having a risk factor does not automatically mean that you will develop cancer, but they do increase the likelihood of it happening.

Knowing your risk factors and talking about them with your doctor may help you make more informed lifestyle and health care choices.

Some risk factors are environmental and within your control which is why it is important to understand what they are.

Gallbladder cancer | Mate Pukupuku kouawai


Gallbladder cancer usually occurs in people who have gallstones. Gallbladder cancer does not usually cause symptoms until it becomes more advanced, however, it may be discovered at an earlier stage due to pain from the gallstones. Gallbladder cancer is sometimes diagnosed unexpectedly when the gallbladder has been removed to treat gallstones. It’s important to note that gallstones are a very common condition and that the majority of people with gallstones do not develop gallbladder cancer.

Other risk factors include:

  • primary sclerosing cholangitis

  • family history of gallbladder cancer

  • inflammation of the gallbladder, gallstones or gallbladder polyps

  • porcelain gallbladder

  • abnormalities of the pancreas and bile duct

  • diabetes

  • smoking and excessive alcohol

  • being overweight.

Bile Duct Cancer (also known as cholangiocarcinoma) | Mate pukupuku pūwaiate

Chronic inflammation of the bile ducts (primary sclerosing cholangitis) predisposes a person to bile duct cancer, but it can also occur in the absence of this condition.

Other risk factors include:

  • primary sclerosing cholangitis

  • ulcerative colitis

  • choledochal cysts

  • liver fluke infection

  • bile duct stones

  • liver cirrhosis

  • hepatitis B or C virus infection.

Ampullary cancer

Risk factors for ampullary cancer include:

  • cholecystectomy

  • familial adenomatous polyposis

  • smoking

  • being overweight.

Diagnosis

Tautohunga


Diagnosing gallbladder and bile duct cancer | Te tautohunga i te mate pukupuku kouawai, pūwaiate

Being diagnosed with cancer can be a scary time for anyone. Here you will find information to help you understand some of the terms you might have heard.

Your cancer may be initially diagnosed by your surgeon or gastroenterologist who will then discuss this with the multidisciplinary team (MDT) including other specialist doctors such as oncologists, radiologists, pathologists. They will also request a series of tests or scans, some of which are described in the information below. Once a diagnosis is confirmed they will explain to you what type of cancer you have and what stage it is (how far it has spread in your body from where it first started).  If needed they will make a referral to other specialist doctors such as oncologists who will discuss the prognosis and how it will be treated.

Computed tomography (CT) scan | Matawaitanga-ā-rorohiko

A computerised tomography scan (CT scan) combines a series of x-ray images that are taken from different angles around the body. You will lie on a motorised bed that passes through a doughnut shaped tube. It is important that you lay still for good quality images to be taken and so a strap and/or pillows may be used to help with this. It isn’t painful and usually takes about 1 hour in an outpatient setting. 

To prepare for the scan, you may be asked to:

  • stop eating or drinking for 4 hours before your scan 

  • take off some or all of your clothing and wear a hospital gown for the scan

  • remove all objects such as jewellery, piercings, dentures, and glasses as they will interfere with the picture quality.

A CT scan uses small amounts of radiation. This is greater than the amount you would get during a simple x-ray, however it is still a small amount and so the risk to your health is very low. The low dose of radiation you are exposed to during a CT scan has not been shown to cause harm.

Click here for an example of a CT scan

Magnetic resonance imaging (MRI) | Whakaahua ponguru autō

An MRI scan uses magnet fields and radio waves to produce a detailed picture of the body. You will lie on a bed that moves into a tube. It is important that you lay still for good quality images to be taken. It isn’t painful and usually takes between 15 and 90 minutes in an outpatient setting. An MRI scan is very noisy and so you may be given headphones to wear. For those who do not like small spaces it may cause some anxiety. If this is the case, speak to your doctor before your MRI as they may be able to provide you with some relaxation tips or medicine to help you feel calmer.

To prepare for the scan:

  • you may be asked to stop eating a few hours before the scan but will be informed beforehand if this is the case

  • take off some or all of your clothing and wear a hospital gown for the scan

  • remove all metal objects such as hair clips and piercings and possibly medical patches if you wear one as they may contain metal.

It is important to tell the radiology staff about any metal you have in your body including possible metal fragments in your eye and metal foreign bodies. Objects that have been implanted in your body need to be discussed ahead of the MRI scan as they may cause harm or be damaged. These include pacemakers, aneurysm clips, heart valve replacements, neurostimulators, cochlear implants, magnetic dental implants and drug infusion pumps.

Click here for an example of an MRI

Magnetic resonance cholangiopancreatography (MRCP) | 

Magnetic resonance cholangiopancreatography (MRCP) is a non-invasive way of viewing the biliary tract and assessing for biliary obstruction to help make decisions on the need for biliary stenting. It is often used in conjunction with an MRI. To prepare for an MRCP you may be asked to stop eating a few hours before the scan. You will be asked to lie on the MRI table and remain very still in order to obtain the best scans possible. The MRI scanner makes a loud humming noise so during the examination you will be able to wear headphones to listen to music of your choice and to hear instructions given to you by the radiographer. Some of the scans will involve you holding your breath for a period of up to 20 seconds. You will be instructed about this beforehand. The total time required for the examination will be about 30 minutes.

Endoscopic ultrasound (EUS) |Oro Ikeike Tiro Oranga Whekau

An endoscopic ultrasound uses a flexible tube with a camera on it (called an ‘endoscope’) which is inserted into the stomach through the mouth and oesophagus (food pipe). It uses sound waves to create images. Sometimes, there is a small needle on the end that can take fluid or tissue samples (a biopsy) that can be analysed later by the lab.

During an upper EUS test, you lie on your left side. A healthcare provider:

  • gives you an IV sedative to help you relax

  • sprays your throat with a numbing medicine

  • places a plastic mouthguard in your mouth. The mouthguard protects your teeth and prevents you from biting down on the endoscope

  • inserts the ultrasound endoscope through your mouth, oesophagus, and stomach until it reaches the duodenum (top part of the small intestine)

  • you shouldn’t feel any pain and you will be able to breathe as usual

  • when the images and/or biopsy have been taken, the healthcare provider gently removes the endoscope and stops anaesthesia. You slowly wake up in a recovery room.

An EUS takes about 1 hour and occurs in an outpatient setting. As you will receive a sedative you will need to take someone with you who can drive you home and stay with you for the remainder of the day.

To prepare for your EUS you may be asked to:

  • adjust the dosage of your medications such as blood thinners or insulin as recommended by your provider

  • not eat or drink for a set period of time before the test

  • take off your clothes on your upper body and change into a hospital gown

Endoscopic ultrasounds are a very safe procedure, but sometimes minor complications may occur. These include:

  1. Sore throat

  2. A small amount of bleeding if a biopsy has been taken

  3. Bloating – as air is sometimes pumped through the endoscope during the procedure

  4. Small tear in the throat – from insertion of the endoscope

  5. Fluid on the lungs – if fluid from your mouth went into the lungs during your procedure

  6. Shortness of breath – due to the effects of the sedative

Positron emission tomography (PET) | Matawaitanga-ā-rorohiko whakarau pūngao

A PET scan uses a special type of camera that detects radioactive material. A small amount of radioactive material is injected into your arm about 1 hour before the scan which will travel and accumulate in areas of the body where there is higher metabolic activity i.e., where there is disease occurring. The body is then scanned to show where the radioactive material is accumulating.

Although not harmful, allergic reactions can occur due to the radioactive material but are extremely rare.

Similar to the CT scan, you will lie on a motorised bed that passes through a doughnut shaped tube. Sometimes the CT scan and PET scan are combined in the same machine and both types of images are taken at the same time. It is important that you lay still on the bed for good quality images to be taken and so a strap and/or pillows may be used to help with this. It isn’t painful and the whole procedure usually takes about 2 hours in an outpatient setting.

After the procedure you naturally pass the radioactive material out of your body in your urine.

To prepare for the scan you may be asked to | Hei whakarite i mua i te whakaata roto ka pātaihia pea i ēnei pātai:

  • avoid strenuous exercise for a couple of days before

  • stop eating 4 hours before your scan.

Click here for an example of a PET scan. *Source: Mediplus.in

Laparoscopy | Poutiro Whekau

Laparoscopy is a type of surgical procedure that allows a surgeon to access the inside of the abdomen (tummy) without having to make large incisions (cuts) in the skin. This procedure is also known as keyhole surgery or minimally invasive surgery. The specialist puts a small tube with a camera on the end (laparoscope), through the cut, into your abdomen which relays images to a television monitor. It can also be used to take biopsies and remove damaged/diseased tissue.

It is done under general anaesthetic (you will be asleep) and usually you can leave hospital the same day or the next day.

The advantages of laparoscopy over traditional open surgery are:

  • a shorter hospital stay and faster recovery time

  • less pain and bleeding after the operation

  • reduced scarring

Laparoscopy is a common procedure and serious complications are rare. Minor complications occur for about 1-2 in every 100 people which may include infection or bleeding around the site.

Click here for an example of a Laparoscopy

Biopsy | Tipako Pītautau

A biopsy is when a small sample of tissue is taken to check under a microscope. The biopsy can be taken at the time of the EUS or laparoscopy.

Click here for a diagram of a biopsy. 

Cholangiography | Iaia waitae tiro kouawai

A cholangiography is when a dye called a contrast medium is put inside your gallbladder and bile ducts which allow any tumours or blockages in the bile ducts to be clearly seen on X-ray. You will be given a sedative and anaesthetic throat spray to numb your throat. A mouth guard is then put into your mouth and a thin flexible tube with a camera and light is inserted into the food pipe until it reaches the small bowel next to the gallbladder and bile ducts. Dye is injected through the pipe which may cause a feeling of fullness on the upper right side of your back. This may feel uncomfortable but should not be painful. An X-ray is then taken, and sometimes a biopsy, where a small sample of tissue is taken for testing. You may feel numbness in your hands and feet during the procedure, but this is perfectly normal.

The procedure usually occurs in hospital and if there are no blockages in the bile ducts you can go home the same day. If there are blockages in the bile ducts, you may have to have a proceedure to insert stents into the ducts to open them up and clear the blockage. this is often done endoscopically, but sometimes requires surgery.

The cholangiography procedure usually takes 30-60 minutes, but you will need to stay in the hospital for about 4 hours afterwards until the sedative has worn off. You will need someone to drive you home and stay with you for the rest of the day.

In preparation for the procedure, you may be asked to:

  • refrain from eating for 6-8 hours beforehand

  • remove your clothes and put on a hospital gown.

There are very few risks for this procedure, but mild side effects may include:

  • sore throat

  • small amount of bleeding – if a biopsy was taken.

After returning home, if you get a high temperature (over 38.5C) you may have a bile leak and or an infection and so you should get back in touch with the hospital.

Endoscopic retrograde cholangiopancreatography (ERCP)

An ERCP is when a long thin flexible tube with a camera on the end is passed through your mouth and stomach to be able to see the bile ducts to detect any blockages. You will be given a sedative and anaesthetic throat spray to numb your throat and a mouth guard is then put into your mouth before the tube is inserted.

The procedure usually occurs in hospital and if there are no blockages in the bile ducts you can go home the same day. If there are blockages in the bile ducts, you may have to have a procedure to insert stents into the ducts to open them up and clear the blockage. This is often done endoscopically but sometimes requires surgery.

The procedure usually takes 30-60 minutes, and you will have to stay in hospital for about 4 hours afterwards until the sedative has worn off. Due to the effects of the sedative, you will need someone to drive you home and stay with you for the rest of the day.

In preparation for the procedure, you may be asked to:

  • refrain from eating for 6-8 hours beforehand

  • remove your clothes and put on a hospital gown.

Click here to view a diagram of an ERCP | Pāwhirihia ki kōnei kia tirohia he hoahoa whakaahuahanga o te ERCP

It's important to acknowledge that some of these tests can be confronting or sometimes frightening. Taking a friend or whānau member with you can help ease anxiety. Be encouraged to tell staff if you need extra reassurance during the test, you'll find some very compassionate people working in healthcare.

Waiting to have tests carried out | E tāria ana kia whakamātauhia

Even if you have been given an urgent referral for a particular scan or investigation you may have to wait several days or possibly weeks for your appointment. This can be frustrating and worrying, especially if you are already feeling unwell.

Several weeks of testing to confirm a diagnosis or awaiting appointments is relatively common and is unlikely to alter overall outcomes. Cancer growth is considered to be negligible over a period of weeks, and this waiting period is unlikely to cause you harm if your symptoms are stable.

If your symptoms get worse or you start to feel more unwell while you are waiting, it is a good idea to get in touch with your GP or specialist if you already have one. If you cannot get in contact with them, you may need to present to the closest emergency department if your symptoms cannot be controlled at home.

How long will I have to wait for my test results | Ka hia te roa e tatari ai kia puta ngā kitenga whakamātautau?

Depending on which tests you have had it may take from a few days to a few weeks for the results to come through. Waiting for test results can be an anxious time. 

It is a good idea to ask how long you may have to wait when you go for tests. If you think you have been waiting too long, then contact your GP or a specialist to follow up on the progress of your results. Usually, the doctor who does the test will write a report and send it to your specialist. If your GP sent you for the test, the results will be sent to the GP clinic. 

You will need an appointment with your specialist or GP to discuss the test results and how they might affect your treatment. Usually, your specialist will discuss your results and plan your subsequent care. 

All these tests will give the specialist more information about the cancer such as where it is, if it is growing, and if it has spread. This is called staging. Staging helps to work out the best treatment plan for you. 

Gallbladder and Bile Duct Cancer Stages | Ngā tūātupu mate pukupuku kouawai me te pūwaiate

You may have heard people talk about the stages of cancer. Staging provides an indication of the size of the cancer and if it has spread to other areas of the body and contributes to the treatment planning.

There are two ways in which the stage of cancer can be described. One uses numbers (stage 1, 2 etc) and the other uses letters and numbers (T1, N0 M0 etc) also known as TNM (Tumour-Nodes-Metastases) staging. The cancer may be described in one or both ways by your healthcare team.

Click here to learn more about the stages of cancer | Pāwhirihia ki kōnei mō ngā kōrero āpiti.

TNM (Tumour-Nodes-Metastases) staging | Tūātuputanga o te Pukupuku, tīpona, tīrara

The TNM gives a number according to tumour size (T), how many lymph nodes are affected (N), and how far the cancer has spread, or metastasised, to distant parts of the body (M). This may be expressed as, for example, T1, N0, M0. This information is used to help decide the best treatment.

TIS           

TIS (carcinoma in situ) means that the cancer is only in the inside lining of the gallbladder or bile duct.

T1

T1 means the tumour has started to grow into the wall of the gallbladder or bile duct.

T1 is subdivided into 2 groups:

  • T1a - the cancer has grown into the connective tissue layer underneath the inner lining of the gallbladder or bile duct wall.

  • T1b - the cancer has started to grow into the muscle layer underneath this connective tissue layer.

T2

T2 - the cancer has grown through the main muscle layer of the wall into the connective tissue underneath.

T3

T3 - the cancer has grown through the gallbladder or bile duct wall. It may have started to grow into the liver or another nearby organ such as the stomach, bowel, or pancreas.

T4

T4 - the cancer has grown into one of the main blood vessels into the liver (the hepatic portal vein or hepatic artery). Or, it has grown into 2 or more organs outside of the liver.

N0

N0 - there are no lymph nodes containing cancer cells.

N1

N1 - there are cancer cells in one to three nearby lymph nodes.

N2

N2 - there are cancer cells in four or more nearby lymph nodes.

M0

M0 - the cancer has not spread to organs or structures far away from the gallbladder.

M1

M1 - the cancer has spread to another part of the body far away from the gallbladder, such as the brain or lungs, sometimes known as distant metastasis.

Staging using numbers | Tūātuputanga ā tau

Stage 0           

Stage 0, also called carcinoma in situ, has abnormal cells in the epithelium. It hasn’t spread to the lymph nodes or other places in the body.

Stage 1

Stage 1 is still localized within the gallbladder, but the tumour has begun to penetrate into the wall of the gallbladder/into the lamina propria and muscle layer.

Stage 2

Stage 2 is divided into 2 subgroups:

  • Stage 2A: Cancer cells have spread through the muscle to the next layer of connective tissue, but not on the side that sits under the liver.

  • Stage 2B: The cancer cells are in the connective tissue on the outside of the gallbladder on the same side as the liver, but they haven’t affected the liver.

Stage 3

Stage 3 has two subcategories:

  • Stage 3A: The cancer has spread through the outer layer of connective tissue to the serosa and/or to the liver or to a nearby organ or structure in the abdomen.

  • Stage 3B: This stage shares stage 3A characteristics, but cancer may also be found in one to three lymph nodes.

Stage 4

Stage 4 is divided into 2 subgroups:

  • Stage 4A: The cancer has spread to the main artery or vein of the liver or to two or more abdominal organs or structures beyond the liver. Cancer cells may have reached nearby lymph nodes, but they haven’t reached distant organs.

  • Stage 4B: Cancers at this stage are the most advanced. Cancer cells have either spread to lymph nodes farther away from the gallbladder, or they have spread to distant organs.

Prognosis (Life expectancy) | Matapaenga (Te wā ora)

Like any cancer there are many things that can impact on survival rates, so it is best to talk to your cancer specialist for guidance about your own care and outcomes.  Remember, even with a diagnosis, no one can know for certain how long anyone will live. Estimates of life expectancy are based on historical data, however treatments are becoming more effective over time which changes these estimates.

Prognosis is usually improved the earlier the cancer is detected. Your doctor will be able to give you the best idea of prognosis.

Often, statistics talk about survival rates which are taken from an average of other patients. These are usually described in 1, 5 and 10-year survival rates. A 10-year survival rate is the proportion (or percent) of people who have not died 10 years after having cancer, however many people live much longer than this.

Click here to view gallbladder and bile duct cancer statistics related to morbidity (number of diagnoses) and mortality (survival rate) | Pāwhirihia kia tirohia ngā tauanga tahumaero me te matenga ā te Mate pukupuku kouawai me te pū waiate. Remember that everyone is different, and statistics are only a guide.

Prognosis depends on the stage and whether or not it is possible to remove the cancer with surgery. In the best circumstances, cure is possible. If cure is not possible, the symptoms caused by the cancer can often be alleviated.

Despite being most common in patients over the age of 60, both gallbladder cancer and cholangiocarcinoma is diagnosed in an increasing number of 45-60-year-olds.

Each year, 185 people are diagnosed with gallbladder and extrahepatic bile duct cancer. That is equivalent to 3.6 people for every 100,000.

The survival rate for gallbladder and extrahepatic bile duct cancer is 32% at one year, 14.3% at year 5, and 12.9% at year 10. Around 130 New Zealanders die from gallbladder and bile duct cancer each year.

Remember that everyone is different, and statistics are only a guide.

Seeking a second opinion | E rapu ana i te whakaaro kē atu

Following diagnosis, some people choose to request a second opinion because they want to have peace of mind that they have explored all options and opinions available to them before starting treatment.

If you would like to know more about your care team and how to seek a second opinion, click here.

Treatment

Ngā momo rongoā


Treatment options | Ngā kōwhiringa rongoā

There are a number of treatment options available, and it may feel confusing and unsettling not knowing which will be the best for you.

Treatment of gallbladder and bile duct cancer depends on its location, the stage of the cancer (how advanced it is at the time of diagnosis), and whether the person is otherwise medically fit.

The choice of treatments will be discussed with you and your whānau and your preferences will be considered. Your treatment will be discussed by a multidisciplinary team (MDT), which means that experts in different areas of cancer treatment (e.g., surgeons, gastroenterologists, radiologists, oncologists, and nurses) come together to share their expertise in order to provide the best patient care.

It is also important to note that more than one treatment may be needed to get the best results.

See below to read more about the treatment options | Tirohia atu ētahi kōwhiringa rongoā ki raro nei.

*Not all the options below will be applicable to everyone's situation. Some treatments listed may not be funded and would require the patient to pay directly. It is important to discuss all your options with your specialist team.

Surgery | Poka tinana

The main treatment for gallbladder and bile duct cancer is surgery where the cancer is surgically removed (cut out).

There are a number of different operations that can be carried out depending on where the cancer is and how far it has spread.

Gallbladder surgery | Pokanga kouawai

The main treatment for gallbladder and bile duct cancer is surgery where the cancer is surgically removed (cut out).

There are a number of different operations that can be carried out depending on where the cancer is and how far it has spread.

Simple cholecystectomy | Tīpokanga heipū o te kouawai

This is where the whole gallbladder is removed. This is done under general anaesthetic with either open surgery (where the abdomen is opened up) or laparoscopic surgery (keyhole surgery).

Extended or open cholecystectomy | Tīpokanga auroa o te kouawai

This is where the gallbladder, lymph nodes and part of the liver are removed if the cancer has spread throughout the gallbladder.

Radical resection | Huke pūtautau tūwhana

This is where the gallbladder and surrounding tissues are removed if the cancer has spread outside your gallbladder to nearby lymph nodes. If your surgeon thinks the cancer has spread to other organs in your body, you may need to have them removed. This can include taking out:

  • the pancreas

  • the duodenum (the beginning of your small bowel)

  • a larger part of the liver

  • any other parts of organs that contain cancer cells, for example the stomach or part of the bowel.

Click here to view a diagram of the surgery | Pāwhihria ki kōnei kia tirohia te hoahoa o te pokanga

Bile duct surgery | Pokanga pūwaiate

Intrahepatic Cholangeocarcinoma | Pukupuku orotā pūwaiate roto

To remove an intrahepatic CCA, the surgeon must remove part of the liver. They will also remove nearby lymph nodes, which can be examined after the operation to see if the cancer has spread. The surgery may leave only a small amount of healthy liver, therefore a procedure called portal vein embolisation (PVE) might be used before surgery to reduce the risk of liver failure after resection. In PVE, blood flow to the area of liver containing the cancer is partially blocked off. This increases the size of the healthy part of the liver that will remain after surgery, by encouraging it to grow.

Hilar Cholangocarcinoma | Pukupuku orotā pūwaiate

Resection of a hilar CCA involves removal of the bile duct containing the tumour as well as the common bile duct, part of the liver, the gallbladder and nearby lymph nodes. Part of the pancreas and duodenum might also be removed. The remaining bile ducts are re-joined to the intestine, and blood vessels that supply the liver might also have to be reconnected. A procedure called portal vein embolisation (PVE) may be offered to patients before resection (see above paragraph for information on PVE).

Extrahepatic Cholangeocarcinoma | Pukupuku orotā pūwaiate waho

Surgery for extrahepatic CCA requires removal of the bile duct containing the tumour, nearby lymph nodes, part of the pancreas and part of the duodenum. The remaining pancreas and stomach are then reconstructed.

Ampullary cancer surgery | Pokanga mate pukupuku pū hono

Ampullary cancer is typically removed by a type of surgery called pancreatoduodenectomy (also known as Whipple’s procedure). This involves removal of the head of the pancreas, part of the small intestine, the gallbladder and part of the bile duct.

Stents | Ngongo roa

Sometimes bile ducts can become blocked by the cancer, causing jaundice, nausea, and discomfort. To relieve some of these symptoms, small tubes called stents can be inserted into the bile ducts to open them up.

Radiation therapy | Haumanu iraruke

Radiation therapy may be used in conjunction with surgery and/or chemotherapy. Radiotherapy is often used in stomach cancer to shrink the tumour, relieve symptoms, and help you feel more comfortable. It is used to control symptoms such as pain and bleeding when surgery is not suitable.

Radiation therapy uses x-rays (ionising radiation) to damage the deoxyribose nucleic acid (DNA) of cancerous cells to kill the cancer cells and stop the cancer growing. It can be given for all stages of cancer.

External beam radiation therapy | Haumanu Iraruke pūhihi rāwaho

Getting radiation therapy is similar to getting an X-Ray but the radiation is stronger. It is a painless procedure which involves lying on a table and a large machine rotating around you. It is directed at the tumour to try to kill the tumour or stop the cancer cells growing without damaging the healthy tissue nearby. Radiotherapy is usually performed in an outpatient clinic. It usually takes place everyday Monday to Friday and lasts for about 10-20 minutes. Your treatment team will be able to tell you how many weeks you will need radiotherapy for. 

Click here to view an example of external beam radiation therapy.

Chemotherapy | Haumanu matū

Chemotherapy uses drugs to kill cancer cells and stop the cancer growing and dividing and may be used in combination with surgery and/or radiotherapy.

Chemotherapy is a drug which is administered either by swallowing tablets; through an injection; or through infusion which is a small tube that is inserted into a vein. The drug works by moving through the blood stream to kill the cancer cells. Unfortunately, some healthy cells can also be harmed leading to side effects. Chemotherapy can be given alone or in combination with other therapies such as targeted therapy, surgery, or radiation. It is usually administered in an outpatient clinic and sometimes a hospital stay is needed if the doctor wants to monitor you following treatment.

Click here to view an example of chemotherapy infusion | Pāwhirihia ki kōnei kia tirohia te hoahoa whāuru haumanu matū.

Clinical trials | Whakamātau haumanu

You may be eligible to take part in a clinical trial, which is a type of research study that investigates new or specialised therapies or treatments. While you are discussing therapy options with your care team, it is a good idea to ask about clinical trials that may be suitable for your condition and discuss whether participating may be right for you. 

Being involved in a clinical trial may be beneficial in that you may access the latest treatments before they become generally available. Additionally, clinical trial participation is often associated with closer monitoring of your care and condition and potentially improved outcomes. 

Clinical trials are free, and travel and accommodation (if needed) are provided. 

Click here to learn more about clinical trials | Pāwhirihia ki kōnei kia tirohia tētahi tauira o te whāuru haumanu matū.

Palliative care | Pairuri

A specialist may refer a patient to palliative care services, but this doesn’t always mean end-of-life care. Today people can be referred to these services much earlier if they’re living with cancer. Palliative care can help one to live as well as possible including managing pain and symptoms. This care may be at home, in a hospital or at another location one prefers. Additional supportive care (treatment or services that support you through a cancer experience) are also available.

Traditional Māori Healing | Rongoā Māori

Rongoā Māori is a body of knowledge that takes a holistic view to wellbeing and treatment. In particular, it focuses on hinengaro (mind), wairua (soul), mauri (life essence), ngā atua (Gods) and te taiao (the environment).

There are many providers who are able to provide rongoā services. Your Māori Health team at the hospital will be able to connect you with one nearest to where you live.

See the below websites for more information on rongoā Māori

Other complementary therapies

Complementary therapies are treatments that are used alongside standard treatments. They are often used to boost the immune system, relieve symptoms, and enhance the effectiveness of standard treatments.

Speak to your doctor if you intend to use complementary therapies to ensure that they will work well alongside your treatment.

Some examples of complementary therapies are:

  • acupuncture

  • meditation and mindfulness

  • music therapy

  • massage

  • aromatherapy

  • naturopathy

  • tai chi

  • pilates

  • visualisation or Guided Imagery

  • spirituality.

Click here to find out more about complementary therapies

Side Effects from Treatment

Ngā mate āpiti


Side effects of gallbladder and bile duct cancer treatment | Ngā mate āpiti o te rongoā mate pukupuku kouawai me te pūwaiate

As with any medical treatment, you may experience side effects from your cancer treatment. This is perfectly normal and can be a sign that the treatment is working, although it may feel unpleasant. Side effects vary from person to person and depend on the type of treatment, the part of the body treated, and the length and dose of treatment. Most side effects are temporary and go away after treatment ends. Below you can find information on some common side effects of treatments and how you can manage them to improve your daily well-being.

You may experience side effects other than those discussed here.

If you experience side effects, let your healthcare team know when you next see them. If the symptoms feel extreme or are worrying you, get in contact with your oncology team sooner.

Common side effects of gallbladder and bile duct cancer treatments | Ngā mate āpiti tōkau o te rongoā mate pukupuku kouawai me te pūwaiate

Click on each treatment to learn more about the side effects of that treatment | Pāwhirihia i ia momo rongoā kia tirohia i ngā mate āpiti e hāngai ana

Surgery | Poka tinana

How long it takes to recover from a simple cholecystectomy will depend on whether you have had open surgery or laparoscopic surgery.

If you have had laparoscopic surgery, you can usually leave hospital the same day and return to work in 2 weeks (or longer if you have a manual job).

If you have had open surgery, you will usually have to stay in hospital for 3-5 days and can return to work in 3-4 weeks (or longer if you have a manual job).

Symptoms following the surgery may include:

  • swollen, bruised and painful wounds which should start to improve within a few days

  • feeling sick as a result of the anaesthetic but this should pass quickly

  • pain in your tummy and shoulders as a result of the gas used to inflate your tummy and should pass after a couple of days

  • bloating, flatulence, and diarrhoea which may last a few weeks.

 If you have had an open cholecystectomy or radial resection, you may have a wide range of symptoms depending on the tissue and/or organs that have been removed.

Chemotherapy and biological therapies | Haumanu matū, koiora

Chemotherapy treatment kills cancer cells, but in the process, damages normal healthy cells which causes side effects. These side effects vary from person to person and depend on the type of treatment, the part of the body treated, and the length and dose of treatment. Below are some common side effects of this.

  • nausea and vomiting | Whakapairuaki & Whakaruaki

  • loss of appetite | Minangaro

  • feeling full quickly | Pūnaunau wawe

  • diarrhoea and constipation | Kotere me te Kōroke

  • fatigue | Ruha

  • weight loss | Heke taumaha

  • sore mouth or throat | Mamae o te Waha/ Korokoro

  • taste changes | Panonitana rongo tawara

  • hair loss | Whakahewa

  • dry or itchy skin | Kiri mangeo

  • foggy brain.

Some chemotherapy side effects can be life threatening therefore it is important to go to contact your oncology team or go to your nearest emergency department immediately if you experience any of the following and let them know that you are undergoing chemotherapy treatment. These include:

  • fever or chills

  • pain in your chest or difficulty breathing

  • diarrhoea

  • vomiting that is not eased with anti-sickness medication

  • bleeding from the gums or nose that doesn’t stop

  • pain or blood present when passing urine.

Radiation therapy | Haumanu iraruke

Radiation therapy is used to kill cancer cells, but it can also kill some healthy cells near to the cancer site too. Although radiation therapy itself does not hurt, you may experience some symptoms afterwards due to the affect the radiation has on the healthy cells. These symptoms may include:

  • nausea and vomiting | Whakapairuaki & Ruaki

  • loss of appetite | Minangaro

  • feeling full quickly | Pūnaunau wawe

  • diarrhoea and constipation | Kotere & Kōreke

  • fatigue | Ruha

  • similar to a sunburn - at the radiation site | Mamae Tīkākā

  • weight loss | Heke taumaha.

Managing symptoms and side effects | Whakahaere tohumate me ngā mate āpiti

Click on the symptoms below to find information on how to manage symptoms and side effects | Pāwhirihia i ia momo tohumate mō ngā mōhiohio kia whakahaere ai ngā tohumate me ngā mate āpiti

Fatigue | Ruha

A common side effect of treatment is feeling constant tiredness (fatigue). Treatment or the cancer itself can reduce the number of red blood cells in your body, resulting in anaemia, which can make you feel very tired. 

Tips to manage fatigue | Ngā kupu āwhina mō te whakahaere i te ruha:

Use your energy wisely

  • plan ahead for when you feel too tired to cook

  • shop online for groceries

  • bulk cook meals you can store in the freezer

  • cook when you have more energy

  • ask and accept offers of help with shopping and cooking from whānau and friends

  • use home delivery services such as Meals on Wheels or other companies that bring pre-prepared food to you. You can ask for help to access these via your social worker

  • keep snacks handy in your bag or car.

Activity can help with fatigue

  • regular, gentle exercise can help improve fatigue and your appetite

  • activity can mean many things – walking, stretching, even vacuuming!

  • set small goals. Set a timer for five minutes and see what you can manage in this time 

  • eat with others.

Loss of appetite | Kore hiakai

It can be discouraging to lose your appetite. You may lose your appetite because of the effects of cancer itself, the treatment, or other side effects, such as feeling sick, not enjoying the smell of food, or feeling upset. To help you can:

  • eat small amounts often, e.g., every 2–3 hours. Keeping to a regular eating pattern rather than waiting until you are hungry will mean your body gets the nourishment it needs to

  • use a smaller plate – a big plate of food may put you off

  • eat what you feel like when you feel like it. Have cereal for dinner or a main meal at lunch

  • include a variety of foods in your diet

  • sip fluids throughout the day

  • replace water, tea and coffee with drinks or soups that add energy (kilojoules/calories), such as milk, milkshake, smoothies, replacement drinks or soup

  • relax dietary restrictions – maintaining your weight or regaining weight you have lost is more important than avoiding full-fat and other high-energy foods

  • gentle physical activity can stimulate appetite – take a short walk around the block

  • eat with others

  • keep snacks handy e.g., in your bag or car so you can eat on the go

  • talk to your dietitian about liquid meal replacements that might be easier to digest.

Taste or smell changes | Rongo kakara me te hā

Some treatments such as chemotherapy can change the way food and/or drink taste or smell. It may taste bland or metallic. 

Tips on managing changes in taste include:

  • add extra flavour to food if it tastes bland – like fresh herbs, lemon, lime, ginger, garlic, soy sauce, honey, chilli, or pepper

  • experiment with different food, as your tastes may change

  • if meat tastes bad during treatment, replace it with other protein sources like cheese, eggs, nuts, dairy foods, baked beans, lentils, or chickpeas

  • add small amounts of sugar to food if it tastes bitter or salty

  • use a straw when drinking

  • change from using metal cutlery to plastic or bamboo cutlery. 

Tips on managing changes in smell include | Ngā kupu āwhina mō te whakahaere i ngā panoni rongo kakara:

  • eat cold food or food at room temperature (hot food smells more)

  • reheat pre-prepared meals in the microwave so the cooking smell doesn’t put you off

  • stay out of the kitchen, if possible, when food is being prepared

  • ask family or friends to cook

  • use the exhaust fan, open the kitchen window, or cook outside to help reduce cooking smells

Nausea and vomiting | Whakapairuaki me te ruaki

Feeling sick and vomiting are often side effects of cancer, its treatment, or some medicines. They often occur together, but not always. 

Nausea | Whakapairuaki

Nausea is stomach discomfort and the sensation of wanting to vomit. Nausea can be a precursor to vomiting the contents of the stomach and may be caused by treatment, stress, food odours, gas in the gastrointestinal tract, motion sickness or even the thought of having treatment. 

Tips on how to cope with nausea | Ngā kupu āwhina ki te morimori i te whakapairuaki:

  • have a light snack before treatment and wait a few hours before eating again

  • eat small meals 5–6 times during the day. Going without food for long periods can make nausea worse

  • snack on dry or bland foods, e.g., crackers, toast, dry cereals, bread sticks or pretzels

  • choose cold foods or foods at room temperature instead of hot, fried, greasy, or spicy foods

  • eat and drink slowly and chew your food well

  • try foods with ginger, e.g., ginger biscuits, or ginger beer

  • avoid foods that are overly sweet, fatty, fried, spicy, or oily, or that have strong smells

  • brush teeth regularly to help reduce unpleasant tastes that may make you feel nauseated

  • do not eat your favourite food when feeling nauseated to avoid developing a permanent dislike

  • suck on hard lollies – flavoured with ginger, peppermint, or lemon

  • try ginger food and drink items, such as candied ginger, ginger beer, ginger ale, or ginger tea. Talk to your dietitian doctor or pharmacist about ginger supplements

  • take anti-nausea medicines as prescribed. Let the doctor know if the medicines don’t seem to be working. 

Vomiting | Ruaki

Vomiting is the forcible emptying (“throwing up”) of stomach contents through the mouth. Vomiting can follow nausea and may be caused by treatment, stress, food odours, gas in the gastrointestinal tract, motion sickness or even the thought of having treatment.

Vomiting is more serious than nausea. Vomiting can cause dehydration and increase the risk of malnutrition. See a doctor if you are vomiting for more than one day, especially if you cannot keep water down as you may become dehydrated. 

Tips on how to cope with vomiting | Ngā kupu āwhina ki te morimori i te ruaki:

Take small sips of water or clear liquids, such as ginger ale, soda water or sports drinks like Gatorade or Hydrolyte. Dilute sweet drinks. If you feel like a fizzy drink, open it, and let it sit for 10 minutes or so, and drink it when it’s a bit flat

  • sucking on crushed ice cubes or an ice block can be soothing

  • once you can keep clear liquids down try some different drinks, such as consommé and clear broths, weak tea, herbal tea, fruit drinks, beef, and chicken stocks

  • have small, frequent meals and snacks throughout the day

  • introduce bland, starchy foods, such as plain biscuits, bread or toast with honey or jam, peanut butter, rice, yoghurt, or fruit. Attempt small, frequent servings at first

  • consume a little bit more each time until you are eating a well-balanced diet.

Chewing and swallowing | Ngaungau me te horomi

After treatment chewing and swallowing may be difficult and painful. Surgery, radiotherapy, and chemotherapy can cause temporary problems. People with dentures who have lost weight may also find their teeth become loose, which can make eating difficult.

Signs that you are having problems with chewing and swallowing include taking longer to chew and swallow, coughing or choking while eating or drinking, or food sticking in your mouth or throat like a ball. 

Tips on chewing and swallowing | Ngā kupu āwhina mō te ngaungau me te horomi:

  • change how you prepare your food by chopping food up into smaller pieces or pureeing

  • let your doctor know that you are having issues and get a referral to see a speech pathologist and dietitian

  • a speech pathologist can monitor your ability to swallow and suggest modifications to the texture of your food once your ability to swallow and chew begins to improve. A dietitian can ensure you are meeting your nutritional needs.

Mouth changes | Ngā panonitanga o te waha

Some chemotherapy drugs and some pain medicines can make your mouth dry, cause mouth ulcers, or change the amount of saliva in your mouth. A dry mouth can increase the risk of tooth decay and infections such as oral thrush, which will make eating harder.

Ulcers may also be present in your digestive tract, causing discomfort in the stomach or bowel and diarrhoea. 

Tips to lessen discomfort with mouth sores | Ngā kupu āwhina ki te whakamauru i ngā harehare waha:

  • suck on ice cubes

  • eat soft foods – stews, soups, scrambled eggs, and smoothies

  • cold foods and fluids may be more comfortable than hot ones

  • avoid ‘coarse’ foods that can irritate your mouth, such as crackers, toast, nuts, and seeds

  • avoid spicy or very hot foods

  • use a straw and direct liquids away from the areas where mouth sores are most painful

  • talk to your doctor about medication or mouth washes to help manage the pain and allow you to eat more comfortably. 

Tips to relieve a dry mouth | Ngā kupu āwhina ki te whakamauru i te waha maroke:

  • suck on ice cubes

  • keep your mouth clean with regular mouthwashes to prevent infections

  • gargle with 1⁄2 tsp salt or 1 tsp bicarbonate of soda in a glass of water

  • choose an alcohol-free mouthwash to avoid irritating your mouth further

  • use a soft toothbrush when cleaning your teeth

  • ask your dentist or health care team about suitable mouth rinses or oral lubricants

  • limit alcohol and coffee as these are dehydrating fluids and avoid smoking

  • avoid ‘coarse’ foods that can irritate your mouth, such as crackers, toast, nuts, and seeds

  • avoid spicy or very hot foods

  • soften food by dipping it into milk, soup, tea, or coffee

  • moisten with sauce, gravy, cream, custard

  • sip fluids with meals and throughout the day

  • chew sugar-free gum to stimulate the flow of saliva.

Changes in bowels- constipation and diarrhoea | Ngā panonitanga o ngā kōpiro

Living with cancer and its treatments can result in changes to your bowel habits. This could be differences in the appearance, consistency, and/or the smell of your stools.

Constipation |  Kōroke

This is when your bowel motions are infrequent and difficult to pass. It can be caused by different factors including regularly taking opioid medicines; having a diet low in fibre; not getting enough exercise; not having enough fluids to drink (dehydration); or having a low overall food intake. 

Tips on how to manage constipation | Ngā kupu āwhina mō te whakahaere kōroke:

  • soften stools by drinking 8–10 glasses of fluid a day, e.g., water, herbal tea, milk-based drinks, soup, prune juice

  • eat foods high in fibre, e.g., wholegrain breads, cereals, or pasta; raw and unpeeled fruits and vegetables; nuts and seeds; legumes and pulses

  • if you are increasing the amount of fibre in your diet, increase fluids to prevent the extra fibre making constipation worse

  • ask your doctor about using a laxative, stool softener and/or fibre supplement

  • exercise – check with your doctor, exercise physiologist or physiotherapist about the amount and type of exercise that is right for you.


Diarrhoea | Kotere

This means your bowel motions are watery, urgent, and frequent. You may also get abdominal cramping, wind, and pain. Frequent loose stools can occur because you are not digesting food or absorbing nutrients properly. Cancer treatment, medicines, infections, reactions to certain foods and anxiety can all cause diarrhoea.

Diarrhoea can result in dehydration, so it’s important to stay hydrated by drinking extra fluids. Every time you have a loose bowel movement you should drink an extra cup of non-caffeinated fluid. If you have diarrhoea for several days, see your doctor so he/she can determine the cause and help to manage your diarrhoea. Your doctor may decide to prescribe you anti-diarrhoea or over-the-counter medication. 

Tips on how to manage diarrhoea | Ngā kupu āwhina mō te whakahaere kōtere:

  • drink plenty of fluids to avoid becoming dehydrated. Water and diluted cordials are better than high-sugar drinks, alcohol, or caffeinated fluids – remember signs of dehydration are smaller amounts of dark urine

  • choose low-fibre foods, e.g., bananas, mashed potato, rice, pasta, white bread, oats, steamed chicken without the skin, white fish

  • avoid foods that increase bowel activity, e.g., spicy, fatty, or oily foods, caffeine, alcohol, or artificial sweeteners

  • try soy milk or lactose-free milk if you develop a temporary intolerance to milk (lactose)

  • don’t eat too many raw fruit and vegetable skins and wholegrain cereals as they may make diarrhoea worse

  • avoid foods and drinks that are high in sugar, such as cordial, soft drinks and lollies

  • avoid foods sweetened with artificial sweeteners such as sorbitol, mannitol, and xylitol. These are often marketed as ‘sugar-free’

  • it may also help to eat small, frequent meals throughout the day, rather than three large meals.

Heartburn (Indigestion) | Tokopā

Some cancers and treatments can cause heartburn, which is a burning sensation in the upper chest, oesophagus and/or throat. It is caused by the contents of the stomach coming back up into the oesophagus (reflux).

Heartburn may make you feel too uncomfortable to eat much, which could lead to weight loss. If the tips below do not relieve heartburn, let your doctor know as medication may help to prevent or manage these side effects. 

Tips to manage heartburn | Ngā kupu āwhina mō te whakahaere tokopā:

  • avoid large meals; try to eat 3 small meals and 3 small snacks throughout the day

  • eat slowly and take the time to enjoy your meal

  • avoid wearing tight clothing while eating, especially belts

  • sip fluids between meals, rather than drinking large amounts at mealtimes

  • limit or avoid foods that may make heartburn worse, e.g., chocolate, highly seasoned spicy foods, high-fat foods (e.g., fried food, pastries, cream, butter, and oils), tomato and tomato products, citrus fruits, coffee (including decaf), strong tea, soft drinks, and alcohol

  • straight after eating, sit upright for at least 30 minutes and avoid lying down or activities that involve bending over (e.g., gardening).

Peripheral neuropathy | Pūtau Iotaiaki mōwaho:

Peripheral neuropathy is caused by damage to the peripheral nerves. These are the nerves in the body outside the brain or spinal cord. Peripheral neuropathy may be caused by cancer, cancer treatments or other health problems. It most commonly affects the hands and feet. Peripheral neuropathy caused by cancer treatment will get better over time with proper treatment and care. 

The most common symptoms of peripheral neuropathy can include | Ngā kōrero tōkau mō te Pūtau Iotaiaki Mōwaho:

  • Tingling, burning, numbness or pain in the hands or feet

  • Difficulty doing up buttons and picking up small items

  • Loss of feeling especially in the hands and feet

  • Problems with balance or walking, and clumsiness

  • Be safe. If you notice changes in your walking, stance, fine and gross motor skills, or balance speak to your doctor as soon as possible and ask for a referral to an occupational therapist, exercise physiologist or physiotherapist 

Tips to manage peripheral neuropathy | Ngā kupu āwhina mō te whakahaere Pūtau Iotaiaki Mōwaho:

  • Use a night light so that you don’t trip or bang into anything if you need to go to the toilet at night

  • Keep clutter and rugs off the floors

  • Have clear paths to the toilet and bedroom

  • Use handrails where possible

  • Use nonslip mats in the shower and bathroom

  • Be careful on slippery and wet floors

  • Do not walk around bare footed as you may not notice if you stand on something that could damage your feet

  • Wear shoes and slippers that fit well

  • Use a walking stick if you need to

  • Wear gloves when washing up, cleaning and gardening

  • Test water temperature with your elbow

  • Take care when cutting food and opening cans or jars

  • Keep your skin moisturised to prevent cracking

  • Check your hands and feet daily for signs of injury, rubbing, redness or infection

  • Ask for help if you need it, e.g., to do up buttons and shoes

  • Find clothes and shoes that are easy to put on and take off

  • Avoid driving if symptoms are severe

Alerting your healthcare team of side effects | Whakaohititia tō rōpu tiaki hauora ki ngā mate āpiti

Your health care team wants to hear about your side effects. Your questions and concerns are important. Do not be afraid to share them. Ask your health care team who you should contact if you feel that your side effects need assessing right away.

Treatment changes | Ngā pānonitanga maimoa

Occasionally, if you have severe side effects, your doctor may discuss delaying or changing your treatment to prevent further discomfort.

Start a symptom diary | Tīmatahia he rātaka tohumate

Keeping track of your symptoms can help you and your cancer care team to manage them better.

Know who to contact if you have a problem | Me mōhio hoki ki te whakapā atu ki a wai mēnā he raru tāu

Ask your doctor or nurse:

  • when you should call for help or advice

  • who you should contact

  • how to contact them (including at night or weekends)

Keep this information where you can easily find it.

Our partners at the Pancare Foundation have created a webinar to help patients manage these side effects and help you navigate each day and experience greater quality of life. Pancare's experts share their knowledge surrounding common side effects such as nausea, peripheral neuropathy, fatigue, mouth sores, abdominal discomfort and more. Practical ways to manage these side effects are explored along with information regarding the support and care available for you and your family. 

*NB - The PanSupport service mentioned is not available to patients in New Zealand

Diet & Nutrition

Whiringa kai me te taioranga


Why is diet and nutrition important? | He aha e whaitikanga ai te whiringa kai me te taioranga?

You may be feeling that some things are out of your control, however there are a number of actions that you can take to make sure your body is in the best condition to cope with, and heal from, the symptoms and side effects of the cancer and cancer treatments. 

Below you will find detail about why diet and nutrition can make a big difference to the healing process and how you feel.

Why does gallbladder and bile duct cancer affect nutrition? | He aha e whakaaweawe ai te mate pukupuku repetaiaki huka i te taioranga?

Gallbladder and bile duct cancer, and cancer treatments place extra demands on your body. They can also cause you to lose your appetite and energy, putting you at an increased risk of malnutrition. It is important to ensure that your body is receiving the right nutrition before, during and after treatment to be able to cope with these extra demands.

Your food choices when you have cancer and are undergoing treatment may be very different from what you are used to eating.

The main goal is to try to keep your weight constant, maintain muscle strength, maintain a healthy weight, and have more energy, all of which help your body to heal properly, improve your quality of life and give you the energy to cope with all the new challenges treatment may bring. 

Gallbladder and bile duct cancer and the treatments for gallbladder and bile duct cancer may impact:

  • your nutritional requirements and what you need to eat

  • how much you eat

  • your appetite

  • your ability to digest food

  • your ability to maintain your weight and muscle mass

  • your energy levels and general wellbeing.

Good nutrition can help to | He mea āwhina te taioranga pai ki te:

  • manage the side effects of treatment

  • speed up recovery after treatment

  • heal wounds and rebuild damaged tissues after surgery, radiotherapy, chemotherapy, or other treatment

  • improve the body’s immune system and ability to fight infections. 

Overall, try to make food choices that provide you enough: | Nā reira, me ngana ki te whiriwhiri i ngā kai ka whakaratoa ki a koe:

  • calories (to maintain your weight)

  • protein (to help rebuild tissues that cancer treatment may harm)

  • nutrients such as vitamins and minerals

  • fluids (essential for your body’s functioning). 

Exercise can also help with appetite and digestion issues related to treatment.

Nutritional tips during treatment | He kupu āwhina taioranga e koke ai te maimoatanga

Click here to learn more about nutritional tips during treatment | Pāwhirihia ki kōnei mō ētahi atu whakamōhiotanga

To maintain good nutrition | Kia mau roa ki te taioranga pai:

  • you may need more energy (kilojoules/calories)

  • eat small, frequent meals or snacks, rather than three large meals a day

  • ask for a referral to a dietitian – discuss eating issues, weight issues, muscle loss

  • do some light physical activity, such as walking, to improve appetite and mood, reduce fatigue, help digestion, and prevent constipation

  • check with your doctor or dietitian before taking vitamin or mineral supplements or making other changes to your diet

  • relax dietary restrictions, e.g., choose full-cream rather than low-fat milk

  • consider using nutritional supplements if you cannot eat enough – discuss options with your doctor, palliative care specialist or dietitian.

Nutritional tips following surgery | Ngā kōrero āwhina taioranga whai muri i te pokanga

Click here to learn more about nutritional tips following surgery | Pāwhirihia ki kōnei mō ētahi atu kupu āwhina taioranga

Surgeries used to treat cancer may result in a variety of side effects, including weight loss and diarrhoea. The side effects usually only last for a short period of time, but you may have to make some changes to your diet to ensure that you are getting enough nutrition and maintaining your weight.

Your body needs good nutrition after surgery, and it is an important part of your recovery process. If you are struggling to eat or drink, the hospital may prescribe nutrition supplements, or recommend tube feeding, to help you to maintain weight and provide you with the nutrients you need for speedy recovery.

Tips on maintaining weight after surgery | Ngā kupu āwhina ki te whakataki taumaha whai muri i te pokanga:

  • monitor your weight – weigh yourself once or twice a week to monitor for any weight loss

  • if you are losing weight, tell your doctor and get a referral to see a dietitian

  • eat small, frequent meals after surgery so your digestive system only has to deal with a small amount of food at a time.

We recognise that dietary changes have a huge impact on everyone with cancer. It can take a while to get used to changes to your diet and lifestyle but finding ways to manage your diet and symptoms can help you feel more in control. It can also be helpful to speak to your dietitian, doctor or nurse.

Living well with cancer

Kia ora pai ai


Learn more about living with cancer.

Read about other people’s cancer journeys see our personal journeys page.