Oesophageal Cancer Stories
5-Fluorouracil (5-FU) is one of the most common chemotherapy drugs used in the treatment of oesophageal cancer. However, every year hundreds of Kiwis suffer debilitating, and potentially life-threatening toxicity from 5FU Chemotherapy treatment. THYmine 2 is investigating a new test that could identify at-risk patients before they start their treatment. Thanks to Gut Cancer Foundation supporters, we have funded the vital role of the clinical trials manager.
574 patients across 70 sites in 8 countries and 3 continents have been recruited to the TopGear clinical trial. TopGear is a vital trial to determine the best combination of chemotherapy, radiotherapy and surgery to improve cure rates for patients with gastric (stomach and oesophageal) cancer. After 12 years, TopGear has completed patient recruitment.
Thanks to Gut Cancer Foundation supporters, New Zealanders have had access to this trial and the support has ensured New Zealand has played an important role in this international collaboration. The length and breadth of TopGear shows just how complex it can be to successfully create and recruit to clinical trials.
Our colleagues at the Australasian Gastro-Intestinal Trials Group (AGITG) have done an incredible job to bring this trial to completion, and we are grateful to our supporters for helping New Zealand play its part.
With the trial moving into its final stages, we look forward to keeping you updated with the trial’s findings as results are made available.
For more information on this trial and others being enabled by your support, click here.